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Bempedoic Acid: A New Option for Statin-Intolerant Patients and Unicity Balance as a Natural Cholesterol-Lowering Alternative

cholesterol clinical studies heart disease unicity balance Apr 15, 2023
A woman reads the medication insert while holding the package in one hand, standing over her husband who holds a packet of the medication and a glass of water. The image text reads 'Exploring Cholesterol Lowering Alternatives.

High cholesterol is a major concern for many people, especially those at risk for heart disease. Statins are often prescribed to lower "bad" cholesterol (LDL-C), but some patients cannot tolerate these medications.

In this article, we will discuss a recent study on bempedoic acid, a new cholesterol-lowering drug for statin-intolerant patients sold under the brand name Nexletol among others, its potential side effects, and introduce Unicity Balance, a natural alternative listed in the Physician's Desk Reference (PDR) for Healthy Cholesterol Support.

Bempedoic Acid: A Promising Alternative for Statin-Intolerant Patients

A new study published in the The New England Journal of Medicine titled "Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients" examined the effectiveness and safety of bempedoic acid for patients who cannot tolerate statins. The research involved 4,025 participants with a history of heart and blood vessel diseases or at high risk of developing them and had experienced statin intolerance.

The study aimed to determine if bempedoic acid could help prevent major heart-related events, such as nonfatal heart attacks, nonfatal strokes, coronary revascularization, or death due to heart-related issues. Participants were given either bempedoic acid or a placebo.

The results showed that bempedoic acid lowered LDL-C levels by 21% after 12 weeks and by 18% after 52 weeks compared to the placebo. It also reduced the risk of major heart-related events by 21% compared to the placebo. Although some side effects were reported, there were no significant differences in severe side effects or the number of people who stopped taking the treatment.

Potential Side Effects of Bempedoic Acid

As with any medication, bempedoic acid may cause side effects. Some potential side effects include Common adverse effects in clinical trials were muscle spasms (3.6% of treated patients, as compared to 2.3% under placebo), pain in the back (3.3% versus 2.2%) or in a limb (3.0% versus 1.7%), gout (1.5% versus 0.4%), and gastrointestinal problems such as diarrhea. A less common but more serious adverse effect was tendon rupture in the rotator cuff of the shoulder, the biceps tendon or the Achilles tendon.

It is important to note that not everyone who takes bempedoic acid will experience these side effects, and some people may experience side effects not listed here. Patients should consult their healthcare provider if they experience any concerning symptoms while taking bempedoic acid.

Unicity Balance: A Natural Cholesterol-Lowering Alternative Listed in the PDR

For those seeking a natural alternative to manage their cholesterol levels, Unicity Balance may be a viable option. This product contains a blend of natural ingredients designed to promote healthy cholesterol levels and support overall cardiovascular health. Unicity Balance is listed in the Physician's Desk Reference (PDR) as a formula for Healthy Cholesterol Support, providing doctors with a reliable reference for this natural alternative.

A study conducted by the Cleveland Clinic supports the effectiveness of Unicity Balance for cholesterol management. The research found that participants experienced a significant reduction in LDL-C levels after using Unicity Balance for 12 weeks. This suggests that Unicity Balance could be an effective natural alternative for individuals looking to manage their cholesterol levels without the use of prescription medications.

Incorporating Unicity Balance into a heart-healthy lifestyle that includes regular exercise, a balanced diet, and stress management can potentially improve cardiovascular health and reduce the risk of heart-related issues.

Final Thoughts and Considerations

The recent study on bempedoic acid offers hope for statin-intolerant patients seeking an alternative cholesterol-lowering medication. However, it is essential to consider the potential side effects before choosing this treatment option. For those who prefer a more natural approach, Unicity Balance, listed in the PDR and supported by the Cleveland Clinic study, may provide an effective solution for managing cholesterol levels and promoting overall cardiovascular health.

It is important to consult with a healthcare provider before starting any new treatment, whether it's a prescription medication or a natural supplement, to ensure it is suitable for your individual needs and health conditions. By exploring these different options, patients can work with their healthcare providers to find the best course of action for maintaining healthy cholesterol levels and reducing the risk of heart-related issues. Doctors can refer to the Physician's Desk Reference to further investigate the benefits of Unicity Balance as a natural alternative for Healthy Cholesterol Support, providing them with a reliable resource to make informed decisions for their patients' health.

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